Wrocław, Poland
3 - 7 May 2014

Scientific Programme

3 May 2014
09:00 17:00  Pre-congress courses - please see seperate webpages for details
12:00 20:00  Registration
15:00 17:00  Industry Sponsored Satellite Symposia
17:30 19:30  ECE 2014 Opening Ceremony
AUDITORIUM
Chair: P Bouchard (France) ESE President
17:30WE1Welcome to Wroclaw & ECE 2014
   
17:55 18:45  Geoffrey Harris Prize Lecture
AUDITORIUM
Chairs: P Bouchard (France) & B Jarzab (Poland)
GH1Did the hand, then, of the potter shake?
A Grossman (UK)
   
18:45 19:30  European Journal of Endocrinology Prize Lecture
AUDITORIUM
Chair: JA Romijn (The Netherlands)
18:45EJE1Adrenocortical carcinoma - current conepts and future persepctives
M Fassnacht (Germany)
   
19:30 21:00  ECE 2014 Welcome Reception
FOUNTAINS
4 May 2014
07:00 20:00  Registration
08:30 09:15  Plenary Lecture 1
AUDITORIUM
Chair: J Castano (Spain)
PL1Genes, environment and endocrine disease
J Ordovas (USA)
   
09:15 09:30  Presidential Address
AUDITORIUM
Chair: P Bouchard (France)
09:35 11:05  Symposium 1: Endocrine changes and treatment needs in critically ill patients
MULTI ROOM
Chairs: G Van den Berge (Belgium) & J Nauman (Poland)
09:35S1.1Thyroid dysfunction in critically ill patients: to treat or not to treat?
G Iervasi (Italy)
   
10:05S1.2Adrenal dysfunction in critically ill patients
G Van den Berghe (Belgium)
   
10:35S1.3Treatment of diabetes in critically ill patients: rationale and glycemic target
F Dotta (Italy)
   
09:35 11:05  Symposium 2: Pituitary development – from basic research to clinical practice
CONFERENCE ROOMS A&B
Chairs: E Hatipoglu (Turkey) & M Bolanowski (Poland)
10:05S2.1Stem/progenitor cells in the pituitary
C Alvarez (Spain)
   
10:05S2.2Gonadotrope plasticity at cellular and population levels
U Boehm (Germany)
   
10:35S2.3Management of adult patients with disorders of pituitary development
D Kastelan (Croatia)
   
09:35 11:35  Symposium 3: News from thyroid hormones: central transport, energy control and oxidative stress
CONFERENCE ROOMS C&D
Chairs: J Kohrle (Germany) & A Lewinski (Poland)
09:35S3.1Neuro-glial functional coupling in deiodination mediated thyroid hormone signaling
B Gereben (Hungary)
   
10:05S3.2Novel aspects of thyroid hormone transport in the brain
H Heuer (Germany)
   
10:35S3.3Oxidative damage due to macromolecules in the thyroid gland – experimental evidence
M Karbownik-Lewinska (Poland)
   
09:35 11:05  Symposium 4: Endocrine Nurses Session 1: Craniopharyngioma
IMPERIAL HALL - CENTENNIAL HALL
Chairs: C Follin (Sweden) & S Neggers (The Netherlands)
09:35S4.1Challenges in the management of patients with Craniopharyngioma
H Mueller (Germany)
   
10:05S4.2The role of the Endocrine Nurse in the long-term care and treatment of patients post diagnosis of Craniopharyngioma
K Clark (USA)
   
10:35S4.3Psychological aspects of living with a pituitary-related condition
S Jackson (UK)
   
09:35 11:05  Symposium 5: Obesity Beyond BMI
AUDITORIUM
Chairs: D Micic (Serbia) & M Szelachowska (Poland)
09:35S5.1Expandability of adipose tissue and clinical implications
A Vidal-Puig (UK)
   
10:05S5.2Relevance of body composition analysis
J Gomez-Ambrosi (Spain)
   
10:35S5.3Are metabolically healthy obese individuals really healthy?
M Bluher (Germany)
   
11:05 11:25  Coffee & Exhibition
EXHIBITION & POSTER HALL - CENTENNIAL HALL
11:25 13:00  Meet the Expert
11:25MTE1Genetic screening in pituitary patients
CONFERENCE ROOMS A&B
A Beckers (Belgium)
   
11:25MTE2Clinical management of paragangliomas
MULTI ROOM
E Corssmit (The Netherlands)
   
11:25MTE3Premature ovarian insufficiency
IMPERIAL HALL - CENTENNIAL HALL
S Christin-Maitre (France)
   
11:25MTE4Use of zebrafish, teleost model recapitulating the mammalian molecular events during development
CONFERENCE ROOMS C&D
N Tiso (Italy)
   
12:15MTE5The year in the adrenals
MULTI ROOM
M Reincke (Germany)
   
12:15MTE6Role of physical activity in diabetes metabolism - molecular and clinical aspects - how much exercise is needed?
CONFERENCE ROOMS A&B
TBC
   
12:15MTE7Therapeutical dilemmas in NETs
IMPERIAL HALL - CENTENNIAL HALL
B Kos-Kudla (Poland)
   
12:15MTE8Thyroid Quiz
CONFERENCE ROOMS C&D
R Peeters (The Netherlands)
   
11:25 12:15  Debate 1: Glycemic control in type 2 diabetes: 1 - Intensive is beneficial, 2 - Loose is convenient – (Different treatment agents)
AUDITORIUM
Chair: J Christiansen (Denmark)
D1.2FOR
G Bolli (Italy)
   
D1.1AGAINST
L Czupryniak (Poland)
   
12:15 13:00  Lunch & Exhibition
EXHIBITION & POSTER HALL - CENTENNIAL HALL
13:00 14:30  Attended poster presentations: (mandatory attendance)
EXHIBITION & POSTER HALL - CENTENNIAL HALL
13:00 15:30  Endocrine Nurse Session 2: Nurse' Networking Session
Working with Patient Support Groups to improve self-management and education for patients and their families
INDUSTRY SPONSORED
IMPERIAL HALL - CENTENNIAL HALL
Chairs: S Llahana (UK) & M Keil (USA)
13:00EN1.1Welcome to Wroclaw and Endocrine Nursing in Poland
A Rózanska (Poland)
   
13:10EN1.2Best Nursing Poster Award ECE 2013 Presentation: Antenatal Nurse-led Thyroid Clinic
C Goedhart (UK)
   
13:20EN1.3Update on ESE Endocrine Nurses Network activities, announcement of nursing poster presentations and ECE 2014 Best Nursing Poster Award
S Llahana (UK)
   
13:30EN1.4My journey from diagnosis to a full supprt package from clinicians and the Patient Support Group
M Marks de Korver (The Netherlands) - Dutch Addison and Cushing Society
   
13:50EN1.5Working together for better patient care: presentation from a Patient Support Group representative
A Smyth (UK) - Executive Officer for the UK and International Tuner Syndrome Support Society
   
14:10EN1.6Introducing Patient Support Groups at ECE 2014 and group discussion
   
14:50EN1.7Networking, poster display and meeting with the Patient Support Groups
   
14:30 15:30  Oral Communications 1 - 4
14:30 15:30  Oral Communications 1: Thyroid (clinical)
AUDITORIUM
Chairs: TBC & TBC
14:30OC1.1Esophagus motility in overt hypothyroidism
E Tasan (Turkey)
   
14:42OC1.2Levothyroxine substitution in subclinical hypothyroidism: does it have a beneficial effect on all-cause mortality?
M Nygaard Andersen (Denmark)
   
14:54OC1.3Chronic liothyronine (T3) treatment in stable heart failure patients with low T3 syndrome: a randomised, double-blind, cross-over, placebo-controlled intervention study (the LIHFA Study)
P Holmager (Denmark)
   
15:06OC1.4Consequences of experimental hyperthyroidism on brain structure and function in humans
AL Dirk (Germany)
   
15:18OC1.5rh-TSH (Thyrogen) aided radioiodine therapy in children and adolescents with DTC
D Handkiewicz-Junak (Poland)
   
14:30 15:30  Oral Communications 2:Adrenal (clinical)
MULTI ROOM
Chairs: J Salvador (Spain) & TBC
14:30OC2.1Armadillo repeat containing 5 gene (ARMC5) alterations in a large cohort of 98 ACTH-independent macronodular adrenal hyperplasia (AIMAH) patients: genotype/phenotype correlations
R Libé (France)
   
14:42OC2.2Constitutive activation of PRKACA in adrenal Cushing’s syndrome
F Beuschlein (Germany)
   
14:54OC2.3Prognostic value of DNA methylation in adrenocortical carcinomas: an ENSAT study
L Groussin (France)
   
15:06OC2.4Detection of pheochromocytoma by enzyme immunoassay measurements of plasma metanephrines requires appropriately established upper cut-offs of reference intervals
D Weismann (Germany)
   
15:18OC2.5Treatment strategy and outcome with primary aldosteronism: a nationwide longitudinal cohort based study
JJ Wang (Taiwan)
   
14:30 15:30  Oral Communications 3:Neuroendocrinology and signalling
CONFERENCE ROOMS A&B
Chairs: TBC & TBC
14:30OC3.1Constant intravenous infusion of kisspeptin-54 restores LH pulsatility in women with hypothalamic amenorrhoea
C Jayasena (UK)
   
14:42OC3.2Copeptin in the diagnosis and differential diagnosis of diabetes insipidus – the CoSIP Study
K Timper (Switzerland)
   
14:54OC3.3Evidence for interaction between the β2-adrenergic and the insulin receptors
M Vrecl (Slovenia)
   
15:06OC3.4Role of thyroid hormone receptor β expression in lymphangiogenesis in breast carcinoma
O Martinez-Iglesias (Spain)
   
15:18OC3.5NTRK3 receptor expression is strictly associated with medullary thyroid cancer RET mutation status
M Oczko-Wojciechowska (Poland)
   
14:30 15:30   Oral Communications 4:Diabetes and obesity 1
CONFERENCE ROOMS C&D
Chairs: D Schulte (Germany) & TBC
14:30OC4.1The lower postprandial glucose oxidation in non-diabetic carriers of risk variants of TCF7L2 gene
E Adamska (Poland)
   
14:42OC4.2Vildagliptin alone, and in half-dose combination with metformin, attenuates streptozotocin-induced diabetic nephropathy in high-fat fed hemi-nephrectomized rats
V Bayrasheva (Russia)
   
14:54OC4.3Importance of neuropeptide Y as a predictor of nephropathy in type 2 diabetic patients
AL Dogruk Unal (Turkey)
   
15:06OC4.4Endothelial progenitor cells exhibit decreased function but increased numbers in overt type 2 diabetic nephropathy
S Liu (China)
   
15:18OC4.5A comparison of lipoprotein associated phospholipase A2 and high sensitive C-reactive protein levels between diabetic and non-diabetic patients with coronary artery disease
S Das (India)
   
15:30 16:00  Coffee, Posters & Exhibition
EXHIBITION & POSTER HALL - CENTENNIAL HALL
16:00 17:30  Symposium 6: Focus on novel developments of PCOS
AUDITORIUM
Chairs: A Milewicz (Poland) & L Zabuliene (Lithuania)
16:00S6.1Etiopathogenesis of PCOS
E Diamanti-Kandarakis (Greece)
   
16:30S6.2Diagnosis of PCOS
I Lazurova (Slovakia)
   
17:00S6.3Treatment of PCOS
R Pasquali (Italy)
   
16:00 17:30  Symposium 7: Nontumorous pituitary diseases
MULTI ROOM
Chairs: V Popovic (Serbia) & J Marek (Czech Republic)
16:00S7.1New developments in Autoimmune hypophysitis
P Caturegli (USA)
   
16:30S7.2Unusual pituitary infections
S Pekic (Serbia)
   
17:00S7.3Tuberculosis of the pituitary gland
W Drake (UK)
   
16:00 17:30  Symposium 8: Membrane lipid composition and receptor function. Signalling and trafficking
CONFERENCE ROOMS A&B
Chairs: P Varnai (Hungary) & TBC
16:00S8.1Membrane lipid composition and receptor function
T Balla (USA)
   
16:30S8.2Spatiotemporal control of endocytosis by membrane lipids
V Hauke (Germany)
   
17:00S8.3Membrane dynamics in physiology and disease
M Wymann (Switzerland)
   
16:00 17:30  Symposium 9: EYES Session - Cold metabolic inflammation in obesity: ignored complication and treatment target?
CONFERENCE ROOMS C&D
Chairs: E Szczepanek-Parulska (Poland) & D Schulte (Germany)
16:00S9.1Introduction EYES
D Schulte (Germany)
   
16:05S9.2Fertility - PCOS: Metformin
D Rachon (Poland)
   
16:25S9.3CVD - Atheroslcerosis: nanomedicine
F van der Valk (The Netherlands)
   
16:40S9.4Exenatide protects pancreatic islets against brain death-induced inflammation and viability loss
(also presented as Poster 341)
D Crispim (Brazil)
   
17:35 18:20  Plenary Lecture 2
AUDITORIUM
Chair: B Jarzab (Poland)
17:35PL2Advances in molecular pathogenesis of thyroid cancer – therapeutic implications
P Santisteban (Spain)
   
18:30 20:00  Industry Sponsored Satellite Symposia
20:30   ECE 2014 INFORMAL NETWORKING EVENING
5 May 2014
07:00 20:00  Registration
07:00 08:30  Industry Sponsored Satellite Symposia
08:30 09:15  Plenary Lecture 3
AUDITORIUM
Chair: JA Romijn (The Netherlands)
08:30PL3Good times, bad times: (patho)physiology of diurnal rhythms
G Van der Horst (The Netherlands)
   
09:20 10:50  Symposium 10: Difficulties in the treatemnt of Graves' orbitopathy
AUDITORIUM
Chairs: P Rodien (France) & T Bednarczuk (Poland)
09:20S10.1New therapeutic approach
M Salvi (Italy)
   
09:50S10.2Radiotherapy in Graves' orbitopathy - when? how? what for?
M Ruchala (Poland)
   
10:20S10.3When should we perform orbital decompression?
A Eckstein (Germany)
   
09:20 10:50  Symposium 11: Long term outcome of “cured” pituitary patients
MULTI ROOM
Chairs: M Toth (Hungary) & C Badiu (Romania)
09:20S11.1Acromegaly
N Biermasz (The Netherlands)
   
09:50S11.2Quality of life in patients with Non-functioning pituitary adenoma
C Capatina (Romania)
   
10:20S11.3Craniopharyngeoma
H Mueller (Germany)
   
09:20 10:50  Symposium 12 : Gut microbiota in diabetes and obesity
CONFERENCE ROOMS A&B
Chairs: S Lund (Denmark) & J Daroszewski (Poland)
09:20S12.1The gut microbiota and links to metabolic pathologies
O Pedersen (Denmark)
   
09:50S12.2Fecal transplantation
M Nieuwdorp (The Netherlands)
   
10:20S12.3Functional interactions between diet, microbiota and host: effects on intestinal architecture and host nutrient absorption.
T Grenier (Sweden)
   
09:20 10:50  Endocrine Nurse Session 3: Meet the Nurse Expert - Management of Endocrine Emergencies
IMPERIAL HALL - CENTENNIAL HALL
Chairs: AS Nilsson (Sweden) & U Feldt-Rasmussen (Denmark)
09:20EN2.1Meet the Nurse Expert: Management of hypoadrenalism and adrenal crisis
J Van Eck (The Netherlands)
   
09:20 - 10:05Session 1: Hypoadrenalism
   
09:50EN2.2Case presentation of a patient with adrenal crisis
O Ommendal (Norway)
   
10:05 - 10:50Session 2: Thyrotoxicosis
   
10:06EN2.3Meet the Nurse Expert: Management and treatment of the patient presenting with symptoms of thyrotoxicosis
V Fazal-Sanderson (UK)
   
10:35EN2.4Case presentation of a patient with thyrotoxicosis
C Shiotz (Denmark)
   
09:20 10:50  Androgen excess in women and PCOS: conclusions from the PCOS Task Force
CONFERENCE ROOMS A&B
Chairs: E Diamanti-Kandarakis (Greece) & R Pasquali (Italy)
09:20S13.1Laboratory investigation of androgens
M Pugeat (France)
   
09:38S13.2PCOS vs non-classic forms of 21 hydroxylase deficiency
D Pignatelli (Portugal)
   
09:56S13.3Androgen secreting tumors and hyperthecosis
D Macut (Serbia)
   
10:14S13.4Severe insulin resistant states and PCOS
A Gambineri (Italy)
   
10:32S13.5PCOS and cardiometabolic issues
M Pfeifer (Serbia)
   
10:50 11:15  Coffee & Exhibition
POSTER & EXHIBITION HALL - CENTENNIAL HALL
11:15 13:00  MTE
11:15MTE1Repeated - Genetic screening in pituitary patients
MULTI ROOM
A Beckers (Belgium)
   
11:15MTE2Repeated - Clinical management of Paraganglioma
CONFERENCE ROOMS A&B
E Corssmit (The Netherlands)
   
11:15MTE3Repeated - Premature ovarian insufficiency
CONFERENCE ROOMS C&D
S Christin-Maitre (France)
   
11:15MTE9New approaches to investigate dynamic spatiotemporal phosphorylation events (BASIC)
AUDITORIUM
K Tasken (Normay)
   
12:05MTE5Repeated - The year in the adrenals
AUDITORIUM
M Reincke (Germany)
   
12:05MTE6Repeated - Role of physical activity in diabetes and metabolism - molecular and clinical aspects - How much excercise is needed?
MULTI ROOM
TBC
   
12:05MTE7Repeated - Therapeutical dilemmas in NETS
CONFERENCE ROOMS A&B
B Kos-Kudla (Poland)
   
12:05MTE8Repeated - Thyroid quiz
CONFERENCE ROOMS C&D
R Peeters (The Netherlands)
   
12:15 13:00  ESE President meets ESE new members
12:15 13:00  Lunch & Exhibition
EXHIBITION & POSTER HALL - CENTENNIAL HALL
13:00 14:30  Attended poster presentations: P301 - P600 (mandatory attendance)
EXHIBITION & POSTER HALL - CENTENNIAL HALL
14:30 15:30  Oral Communications 5 - 8
14:30 15:30  Oral Communications 5:Adrenal and thyroid
MULTI ROOM
Chairs: Susan Webb (Spain) & M Fassnacht (Germany)
14:30OC5.1Diagnostic and therapeutic outcome in ERCUSYN: preliminary report in over 1000 patients
E Valassi (Spain)
   
14:42OC5.2Relationship between final height and cardiometabolic risk and quality of life in adults with congenital adrenal hyperplasia: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE)
RJ Ross (UK)
   
14:54OC5.3Mitotane induces endoplasmic reticulum stress triggering apoptosis and decrease of steroid hormone synthesis
S Sbiera (Germany)
   
15:06OC5.4MUC-1 – a novel preclinical model for adrenocortical carcinoma?
C Hantel (Germany)
   
15:18OC5.5Validation of follicular thyroid cancer molecular classifier in fine-needle aspiration biopsy samples
M Oczko-Wojcioechowska (Poland)
   
14:30 15:30  Oral Communications 6:Bone, calcium and vitamin D
CONFERENCE ROOMS A&B
Chairs: JA Romijin (The Netherlands) & TBC
14:30OC6.1Ucma as a direct common target of Runx2 and Osterix promotes osteoblast differentiation
JE Kim (Republic of Korea)
   
14:42OC6.2High spontaneous osteoclastogenesis in pediatric osteogenesis imperfecta patients receiving or not intravenous neridronate
M Faienza (Italy)
   
14:54OC6.3Hypoparathyroidism: the burden of illness and impact on patients’ personal lives
B Clarke (USA)
   
15:06OC6.4The REPEAT Study: an open-label clinical trial evaluating the safety and efficacy of recombinant human parathyroid hormone, rhPTH(1–84), for the treatment of hypoparathyroidism in Hungary
P Lakatos (Hungary)
   
15:18OC6.5The effect of recombinant human parathyroid hormone, rhPTH(1–84), on vitamin D metabolism and phosphate homeostasis: results from phase III 24-week REPLACE and phase I clinical studies
ML Brandi (Italy)
   
14:30 15:30   Oral Communications 7:IGF-I and thyroid (basic)
CONFERENCE ROOMS C&D
Chairs: TBC & TBC
14:30OC7.1Growth hormone induces chemoresistance in human endometrial cancer cell lines involving ERK 1/2 and PKCdelta
G Zuolo (Italy)
   
14:42OC7.2The proposed molecular mechanism underlying isolated growth hormone deficiency (IGHD) caused by C53S mutation
M Sander (Germany)
   
14:54OC7.3Targeting the insulin-like growth factor 1 (IGF1R) and insulin (IR) receptors with a dual IGF1R/IR inhibitor, OSI-906, to potentiate mTOR inhibitor effects in experimental models of hepatocellular carcinoma (HCC)
C Pivonello (Italy)
   
15:06OC7.4Training MCT10 to transport thyroxine. Structure based targeted mutations in MCT10
U Schweizer (Germany)
   
15:18OC7.5Direct tri-iodothyronine effects in brown adipocytes
E Schröder (Germany)
   
14:30 15:30  Oral Communications 8:Pituitary (clinical)
AUDITORIUM
Chairs: A Luger (Austria) & J Marek (Czech Republic)
14:30OC8.1Metabolic improvement after treatment of acromegaly is determined by the increase of gynoid fat mass and the decrease of serum vaspin and IGF-I
NC Olarescu (Norway)
   
14:42OC8.2Soluble α-Klotho – a new serum biomarker for the activity of acromegaly
AL Jawiarczyk-Przybylowska (Poland)
   
14:54OC8.3Assessment of atrial electromechanical delay in patients with acromegaly
O Topaloglu (Turkey)
   
15:06OC8.4Normalization of urinary cortisol with the potent 11β-hydroxylase inhibitor LCI699 in patients with Cushing’s disease: 22-week, multicentre, open-label study
B Biller (USA)
   
15:18OC8.5The effects of glucocorticoid treatment on cognition in patients with secondary adrenal insufficiency – results from a RCT
J Werumeus Buning (The Netherlands)
   
15:30 16:00  Coffee & Posters
EXHIBITION & POSTER HALL - CENTENNIAL HALL
16:00 17:30  Symposium 16: Metformin: old dog, new tricks
CONFERENCE ROOMS A&B
Chairs: J Castano (Spain) & V Volke (Estonia)
16:00S16.1Novel mechanisms mediating metformin actions: implications for diabetes and cancer
P Dennis (USA)
   
16:30S16.2Mechanism of antitumoral activity of metformin in thyroid cancer
M Derwahl (Germany)
   
17:00S16.3Antitumoral effects of metformin on cancer stem cells: identification of novel molecular targets
T Florio (Italy)
   
16:00 17:30  Symposium 15: Thromboembolism and contraception
AUDITORUM
Chairs: F Rosendaal (The Netherlands) & W Baranowski (Poland)
16:00S15.1Epidemiology of sex steroid related thromboembolism
G Plu-Bureau (France)
   
16:30S15.2The view of the Hematologist on thromboembolism
F Rosendaal (The Netherlands)
   
17:00S15.3The view of the Gynecologist on thromboembolism
O Lidegaard (Denmark)
   
16:00 17:30  Symposium 14: Clinical outcome of medical intervention in Disorder of Sex Development (DSD)
CONFERENCE ROOMS C&D
Chairs: K Kula (Poland) & E Malecka-Tendera (Poland)
16:00S14.1European study on disorder of sex development
B Koehler (Germany)
   
16:30S14.2Consequences of the preservation of under developed testes in adulthood
J Slowkiwska-Hilczer (Poland)
   
17:00S14.3Hormones responsiveness in germ cells neoplasm
E Rajpert de Meyts (Denmark)
   
16:00 17:30  Symposium 17: Cushing’s syndrome
MULTI ROOM
Chairs: A Grossman (UK) & F Mantero (Italy)
16:00S17.1Is mortality in cured Cushing’s increased or not?
O Dekkers (The Netherlands)
   
16:30S17.2Paediatric Cushing’s
H Storr (UK)
   
17:00S17.3The place of medical therapy in Cushing’s syndrome
J Findling (USA)
   
17:30 18:20  UEMS Update
18:30 20:00  Industry Sponsored Satellite Symposia
20:30   Free evening
6 May 2014
07:00 20:00  Registration
07:00 08:30  Industry Sponsored Satellite Symposia
08:30 09:15  Plenary Lecture 4
AUDITORIUM
Chair: V Lyssenko (Sweden)
08:30PL4Islet transplantation
S Gough (UK)
   
09:15 09:30  UEMS presentation
TBC
09:30 11:00  Symposium 18: Endocrine disease during pregnancy
AUDITORIUM
Chairs: F Kelestimur (Turkey) & A Hubalewska-Dydejczyk (Poland)
09:30S18.1Pituitary tumours during pregnancy
E Mezosi (Hungary)
   
10:00S18.2Pheochtomocytromas/ paragangliomas during pregnancy
M Mannelli (Italy)
   
10:30S18.3Congenital adrenal hyperplasia during pregnancy
K Hagenfeldt (Sweden)
   
09:30 11:00  Symposium 19: Osteoporosis - An update
MULTI ROOM
Chairs: ML Brandi (Italy) & E Sewerynek (Poland)
09:30S19.1Paediatric osteoporosis
W Hogler (UK)
   
10:00S19.2Denosumab: current perspectives
K Briot (France)
   
11:00S19.3Atypical fractures and bisphosphonates in osteoporosis
T Yli-Kyyny (Finland)
   
09:30 11:00  Symposium 20: New hormones and endocrine tissues
CONFERENCE ROOMS A&B
Chairs: V Popovic (Serbia) & TBC
09:30S20.1FGF21, irisin, and other novel players in endocrine metabolic regulation
F Villaroya (Spain)
   
10:00S20.2Products of the ghrelin gene, their role in regulating beta cell and adipocyte function
R Granata (Italy)
   
10:30S20.3The gut: a key organ coordinating the brain control of energy homeostasis
G Mithieux (France)
   
09:30 11:00  Symposium 21: Dilemmas in hormonal replacements
CONFERENCE ROOMS C&D
Chairs: J Wass (UK) & I Lazurova (Slovakia)
09:30S21.1Can we offer androgens in males with a history of prostate cancer?
F Wu (UK)
   
10:00S21.2Can we offer oestrogen replacement therapy in women with breast cancer?
V Baranowski (Poland)
   
10:30S21.3Can we offer GH replacement to patients with a history of malignancy?
R Abs (Belgium)
   
11:00 11:25  Coffee & Posters
EXHIBITION & POSTER HALL - CENTENNIAL HALL
11:25 13:00  MTE
11:25MTE10Pituitary disorders and osteoporosis
CONFERENCE ROOMS A&B
M Bolanowski (Poland)
   
11:25MTE11Bone protection after breast cancer
IMPERIAL HALL - CENTENNIAL HALL
S Orme (UK)
   
11:25MTE12Gestational diabetes mellitus - Definition, aetiological and clinical aspects
CONFERENCE ROOMS C&D
J Francois Gautier (France)
   
11:25MTE13Pituitary apoplexy: diagnosis and management
MULTI ROOM
J Wass (UK)
   
12:15MTE15Erectile dysfunction
CONFERENCE ROOMS C&D
V Vaks (UK)
   
12:15MTE14Real time monitoring of GCPR signalling in living cells (BASIC)
MULTI ROOM
D Calebiro (Italy)
   
12:15MTE16Hyperandrogenism after menopause
CONFERNECE ROOMS A&B
G Kaltsas (Greece)
   
12:15MTE18Diabetes complications, what is new?
AUDITORIUM
P Groop (Finland)
   
11:25 12:15  Debate 3: Androgens perspective for treatment of metabolic syndrome and type 2 diabetes in men
AUDITORIUM
Chair: F Wu (UK)
D3.1AGAINST
A Isidori (Italy)
   
D3.2FOR
H Jones (UK)
   
12:15 13:00  ESE AGM
IMPERIAL HALL - CENTENNIAL HALL
12:15 13:00  Lunch, Posters & Exhibition
EXHIBITION & POSTER HALL - CENTENNIAL HALL
13:00 14:30  Attended poster presentations: P601 - P900 (mandatory attendance)
EXHIBITION & POSTER HALL - CENTENNIAL HALL
14:30 15:30  Oral Communications 9 - 12
14:30 15:30  Oral Communications 9:Reproduction
AUDITORIUM
Chairs: TBC & TBC
14:30OC9.1High frequency of FGFR1 mutations in patients with congenital hypogonadotropic hypogonadism and split hand/foot malformation
C Xu (Switzerland)
   
14:42OC9.2Tadalafil ameliorates metabolic syndrome-induced alterations in visceral adipose tissue and liver: an experimental study in the rabbit
L Vignozzi (Italy)
   
14:54OC9.3Late onset hypogonadism influences the endothelial function in men with coronary artery disease
J Wierzbicka-Chmiel (Poland)
   
15:06OC9.4Kisspeptin – a novel physiological trigger for oocyte maturation in IVF treatment
AL Abbara (UK)
   
15:18OC9.5IGF-1 gene polymorphism in polycystic ovary syndrome
F Akin (Turkey)
   
14:30 15:30   Oral Communications 10:Endocrine tumours
CONFERENCE ROOMS A&B
Chairs: TBC & TBC
14:30OC10.1Blood-borne and tissue microRNAs in adrenocortical tumours: affected pathways and diagnostic relevance
P Igaz (Hungary)
   
14:42OC10.2The cytotoxic effect of sunitinib on human bronchial carcinoid cell lines and primary cultures is counteracted by EGF and IGF-1, but not by VEGF
T Gagliano (Italy)
   
14:54OC10.3The NMU signaling controls cancer progression of human RL95-2 endometrial cancer cells through cell motility maintenance
T Lin (Taiwan)
   
15:06OC10.4Mast cell interactions at tumour interface drive progression in human prostate cancer
G Risbridger (Australia)
   
15:18OC10.5Molecular mechanisms underlying the unexpected promoting effects of mifepristone on murine testicular Leydig cell tumorigenesis
M Chrusciel (Finland)
   
14:30 15:30  Oral Communications 11:Diabetes and obesity 2
MULTI ROOM
Chairs: TBC & TBC
14:30OC11.1Inhibition of cardiac dysfunction in diabetic mice by treatment with brain natriuretic peptide
M Jankowski (Canada)
   
14:42OC11.2An audit of the management of inpatient glycaemia using point of care testing data at Manchester Royal Infirmary
AL Mitchell (UK)
   
14:54OC11.3Improvement or stabilization of retinopathy and visual acuity after islet transplantation: a five-year prospective study
M Vantyghem (France)
   
15:06OC11.4A novel adult human adipose stem cell model from inducible brown fat surrounding pheochromocytoma tumors
AL Di Franco (Italy)
   
15:18OC11.5Lipodystophic laminopathies are characterized by an increased intra/whole abdominal fat ratio with preserved fat/lean mass ratio and hypoleptinemia, in contrast with obese people, compared to controls
K Le Mapihan (France)
   
14:30 15:30  Oral Communications 12:Pituitary (basic)
CONFERENCE ROOMS C&D
Chairs: TBC & TBC
14:30OC12.1Human AIP gene rescue lethality in a Drosophila melanogaster knockout model of AIP orthologue
E Aflorei (UK)
   
14:42OC12.2Differential in vitro response to octreotide and pasireotide in normal and tumoral primary pituitary cell cultures
AL Ibáñez-Costa (Spain)
   
14:54OC12.3Detection of pituitary antibodies by immunofluorescence. Methodological approach and results in patients with pituitary diseases
AL Ricciuti (USA)
   
15:06OC12.4Identification and characterization of pituitary adenoma stem-like cells in human non-functioning pituitary adenomas
E Giardino (Italy)
   
15:18OC12.5Does hypercortisolism of Cushing’s syndrome affect telomere length?
AL Aulinas (Spain)
   
15:30 15:50  Coffee & exhibition
EXHIBITION & POSTER HALL - CENTENNIAL HALL
15:50 17:20  Symposium 22: Novel therapies for thyroid cancer
MULTI ROOM
Chairs: E Puxeddu (Italy) & B Jarzab (Poland)
15:50S22.1Clinical trials and approved drugs
R Elisei (Italy)
   
16:20S22.2Limits of targeted therapies and future developments
S Leboulleux (France)
   
16:50S22.3Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer
J Fagin (USA)
   
15:50 17:20  Symposium 23: Neuroendocrine tumours
AUDITORIUM
Chairs: V Hana (Czech Republic) & B Kos-Kudla (Poland)
15:50S23.1Molecular pathogenesis of neuroendocrine tumours
V Giandomenico (Sweden)
   
16:20S23.2Therapeutic approaches models
S Glasberg (Israel)
   
16:50S23.3systemic therapeutic options
M Pavel (Germany)
   
15:50 17:20  Symposium 24: Nutrient regulation of metabolism and endocrine systems
CONFERENCE ROOMS C&D
Chairs: J Ordovas (USA) & TBC
15:50S24.1Using low-carbohydrate/high fat diets todisect macronutrient effects on endocrine systems
M Bidlingmaier (Germany)
   
16:20S24.2Metabolic Consequences of a High Fat Diet on Mouse Models of Growth Hormone Action
J Kopchick (USA)
   
16:50S24.3The role of FTO in the brain response to different macronutrients
G Yeo (UK)
   
15:50 17:20  Symposium 25: Gonadal hormones and obesity
CONFERENCE ROOMS A&B
Chair: M Tena-Sempere (Spain)
15:50S25.1Oestrogens and body weight
M Lopez (Spain)
   
16:20S25.2PCOS and obesity: unveiling the basic links
U Pagotto (Italy)
   
16:50S25.3Perinatal androgen exposure and body weight fate
E Stener-Victorin (Sweden)
   
17:25 17:45  ESE Young Investigator Awards & Poster Prizes
Industry Sponsored
AUDITORIUM
17:45 18:30  Plenary Lecture 5
AUDITORIUM
Chair: P Bouchard (France)
17:45PL5Simultaneous treatment of menopausal symptoms and prevention of breast cancer: Is it possible?
R Santen (USA)
   
18:30 20:00  Industry Sponsored Satellite Symposia
20:30   ESE President`s Dinner
Invitation only
7 May 2014
07:00 20:00  Registration
08:30 09:15  Plenary Lecture 6
AUDITORIUM
Chair: G Brabant (UK)
08:30PL6Hypothalamic inflammation - cause or consequence of obesity?
C Yi (Germany)
   
09:20 10:50  Symposium 26: Pitfalls in hormone measurement
AUDITORIUM
Chairs: P Beck-Peccoz (Italy) & M Karbownik-Lewinska (Poland)
09:20S26.1Guidelines on GH/IGF-1 measurement
J Frystyk (Denmark)
   
09:50S26.2Pitfalls in thyroid function tests
M Gurnell (UK)
   
10:20S26.3Advantages of mass spectrometry in the measurement of steroid hormones
A Taylor (UK)
   
09:20 10:50  Symposium 27: Brown Adipose Tissue
CONFERENCE ROOMS A&B
Chairs: JA Romijn (The Netherlands) & TBC
09:20S27.1White, brown and pink: plasticity of adipocytes
S Cinti (Italy)
   
09:50S27.2Hunting human brown fat by imaging
P Nuutila (Finland)
   
10:20S27.3Brown adipose tissue: the wholy grail of metabolic disease
J Heeren (Germany)
   
09:20 10:50  Symposium 28: Molecular pathophysiology for clinicians: receptor-related disorders
CONFERENCE ROOMS C&D
Chairs: G Mantovani (Italy) & J Klovins (Latvia)
09:20S28.1Disorders related to G-protein receptors
P Rodien (France)
   
09:50S28.2Disorders related to nuclear receptors
A Aranda (Spain)
   
10:20S28.3Disorders related to calcium-sensing receptor signalling
F Hannan (UK)
   
09:20 10:50  Symposium 29: Obesity prevention and treatment
MULTI ROOM
Chairs: A Vaag (Denmark) & A Milewicz (Poland)
09:20S29.1Mediterranean diet in the prevention of cardiovascular disease
J Salas-Salvadó (Spain)
   
09:50S29.2Rare primary and secondary genetic events in T2D and obesity
P Froguel (France)
   
10:20S29.3Is healthy diet regulated by our genes?
M Orho-Melander (Sweden)
   
10:50 11:20  Coffee break
TBC
11:25 13:00  MTE
11:25MTE19Measuring the utility of exosomes and other membranes vescicles (BASIC)
CONFERENCE ROOMS A&B
TBC
   
11:25MTE10Repeat - Pituitary disorders and osteoporosis
CONFERENCE ROOMS C&D
M Bolanowski (Poland)
   
11:25MTE11Repeat - Bone protection after breast cancer
MULTI ROOM
S Orme (UK)
   
11:25MTE12Repeat - Gestational diabetes mellitus. Definition, aetiological and clinical aspects
IMPERIAL HALL - CENTENNIAL HALL
J Francois-Gautier (France)
   
12:15MTE20Gender specific medicine in endocrinology and metabolism
AUDITORIUM
A Kautzy-Willer (Austria)
   
12:15MTE14Repeat - Real time montoring of GPCR signalling in living cells
MULTI ROOM
D Calebiro (Italy)
   
12:15MTE15Repeat - Erectile dysfunction
CONFERENCE ROOMS A&B
V Vaks (UK)
   
12:15MTE16Repeat - Hyperandrogenism after menopause
IMPERIAL HALL - CENTENNIAL HALL
G Kaltsas (Greece)
   
12:15MTE17Repeat - FGF23 and phosphorus homeostasis: physiology and physiopathology
CONFERENCE ROOMS C&D
JF Navarro-González (Spain)
   
11:30 12:15  Debate 4: Mild primary hyperparalthyroidism surgery or not?
AUDITORIUM
Chair: P Lakatos (Hungary)
D4.1AGAINST
B Niederle (Austria)
   
D4.2FOR
JL Wémeau (France)
   
13:00 13:45  Plenary Lecture 7
AUDITORIUM
Chair: A Spada (Italy)
13:00PL7Reproduction and energy metabolism, an ancestral balance to be preserved for women's health
A Maggi (Italy)
   
13:45 13:50  Farewell & Invitation to Dublin
P Bouchard (ESE President)
AUDITORIUM
14:00   Post-Congress Courses/ Industry Sponsored Satellite Symposia